arcoris bio’s MUSE® technology is a self-assembling, enzyme-free DNA nanotechnology for advanced imaging and biomarker detection. MUSE® works seamlessly with multiple labels – from fluorophores to enzymes like horseradish peroxidase (HRP) – enabling exceptional versatility across applications.
- real simultaneous multiplex imaging of biomarkers
- signal amplification with high signal-to-noise ratio
- easy, ready-to-use workflow with same day results
- no enzymes, no cycles – all steps work at room temperature
- no specialized equipment needed
- automation-friendly design
MUSE® – Multiplex Universal Signal Enhancement
By linking MUSE® activators directly to your biomarker probes (antibodies, Fab fragments, or oligonucleotides), it supports detection of proteins, DNA, and RNA in a wide range of assays, such as immunofluorescence, immunohistochemistry and in situ hybridization.
Combine techniques like IF and FISH with ease — MUSE® makes such multi-method workflows simple.
Effortless workflow: only 2 steps, performed at room temperature, with same-day results and no specialized equipment required.
immunoMUSE® Activate & Amplify kits
Discover our immunoMUSE® Activate & Amplify kits. They deliver high-sensitivity immunofluorescence with no species or isotype constraints – all in one seamless workflow. immunoMUSE® kits are designed for researchers who need more from multiplex staining: more flexibility, more sensitivity, and more confidence in challenging samples.
"We were facing a roadblock caused by target degradation problems while trying to detect two transcipts sequentially with riboprobes and Tyramide Signal Amplification.
Switching to arcoris bio's MUSE nanotechnology allowed us to successfully quantify both targets simply and rapidly thanks to its multiplexed signal amplification and allowed us to conclude our work"
"We needed a solution for sensitive multiplex RNA FISH for a study on human pancreas FFPE sections. Having previously faced complications with other commercial products, we turned to arcoris bio's MUSE nanotechnology. With arcoris bio's efficient assistance and reagents, we rapidly obtained results that matched our expectations and allowed us to finalize our study by complementing our RNAseq data."
Experience the power of MUSE®
We offer off-the-shelf ready-to-use-kits for immunofluorescence, custom solutions for FISH and further applications, as well as licensing and technology integration solutions to our partners.
immunoMUSE® kits
Discover our research kits for multiple IF
Partnerships
Discover our white label & B2B solutions